APEBA, 4- - VUF 10996
Axon 1877
CAS [1226984-28-6]
MF C18H25Br3N2OMW 525.12
- Purity:99%
- Soluble in water and DMSO
Description
Excellent derivatisation reagent for aldehydes and carboxylic acids. Very mild derivatisation conditions. Selectivity for aldehydes or carboxylic acids is obtained by changing co-reagent. In addition to the retained features of the 1st generation reagent 4-APC, 4-APEBA and its adducts contain additional unique properties (Br-isotope identifier, specific bromophenethyl fragmentation, increased lipophilicity).*Sold in collaboration with VU (VU University Amsterdam).
| Kretschmer A, Giera M, Wijtmans M, de Vries L, Lingeman H, Irth H, Niessen WM. Derivatization of carboxylic acids with 4-APEBA for detection by positive-ion LC-ESI-MS(/MS) applied for the analysis (...). J Chromatogr B 2011, 879(17-18), 1393-1401. |
| Eggink M, Wijtmans M, Kretschmer A, Kool J, Lingeman H, de Esch IJ, Niessen WM, Irth H. Targeted LC-MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA. Anal Bioanal Chem. 2010, 397(2), 665-675. |
- Certificate of Analysis
- Material Safety Data Sheet
Chemical name
4-(2-((4-bromophenethyl)dimethylammonio)ethoxy)benzenaminium bromide
Source information
Sold in collaboration with VU (VU University Amsterdam).Parent CAS No.
[1227040-19-8]
Axon Medchem的业务之一，是独有的Axon Ligands配体库，在世界范围内，被认为是药物研发的标准。这其中，针对850余种生物靶标（包括细胞信号、基因转录、凋亡、细胞周期调控、CNS等），Axon Medchem拥有多达2000余种小分子抑制剂或调节剂。除了配体库，Axon Medchem还是欧洲著名的CRO公司，主要针对生物活性分子和药物类似分子展开合成及协议开发工作，在过去的10年中，Axon Medchem已经发现了多种潜在药物分子，并在生物医药界享有一定的声誉。
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