ASP 2905
Axon 2979
CAS [792184-90-8]
MF C20H17FN8MW 388.40
- Purity:98%
- Soluble in DMSO
Description
ASP 2905 is a potent, selective and orally active inhibitor of the potassium channel KCNH3 (Kv12.2) with an IC50 value of 9.0 nM. ASP 2905 may enhance cognitive performance and shows potential in the treatment of attention deficit/hyperactivity disorder.
KEYWORDS: ASP 2905 | supplier | KCNH3 inhibitor | ASP2905 | ASP-2905 | CAS [792184-90-8] | [1246834-45-6] | [578016-50-9] | Potassium | Kv12.2 | Inhibitor | Ion Channels | BEC1 | Dementia | Schizophrenia
| S Takahashi et al. Neurochemical and neuropharmacological characterization of ASP2905, a novel potent selective inhibitor of the potassium channel KCNH3. Eur J Pharmacol. 2017 Sep 5;810:26-35. |
| S Takahashi et al. The KCNH3 inhibitor ASP2905 shows potential in the treatment of attention deficit/hyperactivity disorder. PLoS One. 2018 Nov 21;13(11):e0207750. |
- Certificate of Analysis
- Material Safety Data Sheet
Chemical name
N2-(4-Fluorophenyl)-N4-phenyl-N6-(pyrimidin-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine
Parent CAS No.
[792184-90-8]
Axon Medchem的业务之一，是独有的Axon Ligands配体库，在世界范围内，被认为是药物研发的标准。这其中，针对850余种生物靶标（包括细胞信号、基因转录、凋亡、细胞周期调控、CNS等），Axon Medchem拥有多达2000余种小分子抑制剂或调节剂。除了配体库，Axon Medchem还是欧洲著名的CRO公司，主要针对生物活性分子和药物类似分子展开合成及协议开发工作，在过去的10年中，Axon Medchem已经发现了多种潜在药物分子，并在生物医药界享有一定的声誉。
暂无问答
本网站将在规定时间内给予删除等相关处理。
